Pyroptosis

This volume collects laboratory techniques for studying pyroptosis and keeping pace with current research on it. Its chapters cover experimental ways of triggering pyroptosis through inflammasomes, approaches for detecting inflammasome activation in humans, methods for inducing and detecting pore formation, and techniques for assessing the cellular outcomes of pyroptotic cell death.

The book follows the format of the Methods in Molecular Biology series. Each chapter opens with an introduction to its topic, lists the materials and reagents needed, and gives step-by-step protocols that can be reproduced in the lab. Each also offers advice on troubleshooting and on avoiding known pitfalls.

It is intended for researchers who want to deepen their knowledge of this developing field, and it should be especially useful to those working in immunology, cancer biology, microbiology, and cell biology.